Clinical Relevance of Blood Glucose and Gastroesophageal Reflux Symptoms to Depressive Status in Patients with Type 2 Diabetes Mellitus.

Published on Feb 1, 2020in Acta Medica Okayama0.642
· DOI :10.18926/AMO/57950
Hiroyuki Honda1
Estimated H-index: 1
(Okayama University),
Yoshihisa Hanayama6
Estimated H-index: 6
(Okayama University)
+ 7 AuthorsFumio Otsuka35
Estimated H-index: 35
(Okayama University)
Sources
Abstract
A relationship between diabetes and depression is apparent. To clarify the clinical relevance of diabetic patients' gastroesophageal symptoms to their psychological status, we retrospectively analyzed the data from a Selfrating Depression Scale (SDS) and a Frequency Scale for Symptoms of Gastroesophageal reflux disease (FSSG) among 143 type 2 diabetic patients who visited a general medicine department. Among the 45 Japanese patients enrolled, the group with relatively high SDS scores (>/= 36) showed higher (FSSG) dysmotility symptom scores versus the low-SDS (< 36) group, although the 2 groups' characteristics and laboratory data were not significantly different. Positive correlations of postprandial plasma glucose (PPG) levels with FSSG scores (R=0.321, p<0.05), particularly with reflux scores (R=0.455, p<0.01) were revealed. PPG and HbA1c levels were not correlated with SDS scores. The patients' SDS scores were significantly correlated with their FSSG scores (R=0.41, p<0.01), suggesting that depressive status is linked to GERD-related manifestations. Considering that the patients' PPG levels were correlated with GERD-related symptoms, diabetic patients' blood glucose levels are associated with depressive status. Collectively, key symptoms related to GERD and glucose level values would be helpful.
📖 Papers frequently viewed together
18 Citations
20 Citations
References31
Newest
#1Yu Suganami (Okayama University)H-Index: 1
#2Kosuke Oka (Okayama University)H-Index: 2
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 9 authors...
To clarify the potential relevance of patients' chief complaints at a general medicine department to their self-rating depression scale (SDS) and frequency scale for symptoms of gastroesophageal reflux disease (GERD) (FSSG) scores, we analyzed data of 478 patients who visited our general medicine department. The chief complaints (553 symptoms of 447 patients) were categorized into major symptom-based groups: respiratory (31%), circulatory (3%), gastrointestinal (GI) tract (26%), neurology (8%), ...
3 CitationsSource
#1Robert A. Vigersky (USU: Uniformed Services University of the Health Sciences)H-Index: 4
: The gold standard for monitoring overall glycemia is HbA1c. However, HbA1c has several important limitations, giving more weight to the prior 2 to 3 months rather than short-term glycemic control. In addition, the level of the HbA1c does not reflect the important interpersonal differences in its relationship with mean glucose, and HbA1c is affected by many common clinical conditions (anemia, uremia) that can interfere with the accuracy of its measurement in the laboratory. The development and ...
15 CitationsSource
#1Wen Juan Fan (Peking Union Medical College Hospital)H-Index: 1
#2Yuan Tao Hou (Peking Union Medical College Hospital)H-Index: 1
Last. Xiu Cai Fang (Peking Union Medical College Hospital)H-Index: 2
view all 12 authors...
OBJECTIVES: To investigate the effects of different test meals on esophageal and intragastric pH in patients with gastroesophageal reflux disease (GERD) and healthy subjects and to demonstrate the relationship between esophageal acid exposure (EAE) and gastric pH. METHODS: We enrolled patients with reflux esophagitis (RE; n = 15), nonerosive reflux disease (NERD; n = 12) and healthy subjects (n = 10). Four pH electrodes were used to monitor the pH of the distal esophagus, upper border of the low...
7 CitationsSource
#1Ko Harada (Okayama University)H-Index: 3
#2Yoshihisa Hanayama (Okayama University)H-Index: 6
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 9 authors...
: The aim of this study was to determine the relationships between free testosterone (FT) level and parameters including laboratory data and data from questionnaires and to determine symptoms leading to the detection of late onset hypogonadism (LOH). We retrospectively reviewed medical records of patients in whom serum FT was measured in our hospital. Aging Male Symptoms (AMS) score, self-rating depression scale (SDS) and frequency scale for the symptoms of gastroesophageal reflux disease (FSSG)...
4 CitationsSource
#1Anna Miura (Tokyo Medical and Dental University)H-Index: 5
#2Trang T H Tu (Tokyo Medical and Dental University)H-Index: 5
Last. Akira Toyofuku (Tokyo Medical and Dental University)H-Index: 13
view all 15 authors...
Abstract Objective Atypical Odontalgia (AO) is a condition characterized by tooth pain with no apparent cause. Although psychiatric comorbidity seems to be very common, it has rarely been studied. To clarify the influence of psychiatric comorbidity on the clinical features in patients with AO, we retrospectively evaluated their examination records. Methods Clinical features and psychiatric diagnoses of 383 patients with AO were investigated by reviewing patients' medical records and referral let...
15 CitationsSource
#1Seyed Alireza Haji Seyed Javadi (QUMS: Qazvin University of Medical Sciences)H-Index: 2
#2Ali Akbar Shafikhani (QUMS: Qazvin University of Medical Sciences)H-Index: 2
BACKGROUND: Evidence shows an influence relationship between described symptoms of gastroesophageal reflux disorder (GERD) and emotional state. OBJECTIVE: To determine the relationship between anxiety and depression with GERD in patients referred to the endoscopy unit of Bouali-Sina Hospital in Qazvin. METHODS: This case-control study was conducted in the endoscopy unit of Bouali-Sina Hospital in Qazvin, Iran, from April 2014 through May 2015. Two hundred individuals (100 patients with GERD and ...
21 CitationsSource
#1Shinya Furukawa (Ehime University)H-Index: 26
#2Takenori SakaiH-Index: 8
Last. Yoshihiro Miyake (Ehime University)H-Index: 47
view all 16 authors...
Depressive symptoms and prevalence of erectile dysfunction in Japanese patients with type 2 diabetes mellitus: the Dogo Study
12 CitationsSource
#1Yoshinobu Kanda (Jichi Medical University)H-Index: 38
Although there are many commercially available statistical software packages, only a few implement a competing risk analysis or a proportional hazards regression model with time-dependent covariates, which are necessary in studies on hematopoietic SCT. In addition, most packages are not clinician friendly, as they require that commands be written based on statistical languages. This report describes the statistical software ‘EZR' (Easy R), which is based on R and R commander. EZR enables the app...
6,029 CitationsSource
#1Ayumu Hirata (Osaka University)H-Index: 17
#2Ken Kishida (Osaka University)H-Index: 35
Last. Iichiro Shimomura (Osaka University)H-Index: 26
view all 7 authors...
Background: The prevalence of gastroesophageal reflux disease (GERD) has been increasing worldwide. Abdominal obesity or visceral fat accumulation rather than simple obesity is associated with GERD. Previous reports demonstrated the association between GERD and type 2 diabetes mellitus (T2DM). Signification of visceral fat accumulation and adiponectin in T2DM patients with GERD remains unclear. The present study investigated the relationships between GERD symptoms, visceral fat accumulation and ...
18 CitationsSource
#1Prateek Sharma (KU: University of Kansas)H-Index: 80
#2Sachin WaniH-Index: 68
Last. Frank A. HamiltonH-Index: 31
view all 5 authors...
Gastroesophageal reflux disease (GERD) is a common chronic disorder that is associated with a huge economic burden in the western countries and significantly decreased quality of life. This review focuses on the various multicultural issues in the epidemiology, pathophysiology, diagnosis, and treatment of GERD. The prevalence of GERD appears to be highest in North America and Europe, whereas epidemiologic data from the Indian subcontinent, Africa, South America, and the Middle East are sparse. A...
78 CitationsSource
Cited By0
Newest