Transfontanellar Contrast-Enhanced Ultrasound for Monitoring Brain Perfusion During Neonatal Heart Surgery.

Published on Mar 2, 2020in Circulation-cardiovascular Imaging5.691
· DOI :10.1161/CIRCIMAGING.119.010073
Ferdinand Knieling1
Estimated H-index: 1
,
Ferdinand Knieling8
Estimated H-index: 8
+ 10 AuthorsJörg Jüngert11
Estimated H-index: 11
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Abstract Background Comprehensive information regarding causes of late post-operative death following pediatric congenital cardiac surgery is lacking. Objectives The study sought to analyze late causes of death after congenital cardiac surgery by era and defect severity. Methods We obtained data from a nationwide pediatric cardiac surgery database and Finnish population registry regarding patients who underwent cardiac surgery at Results Overall, 10,964 patients underwent 14,079 operations, with...
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#1Ferdinand KnielingH-Index: 8
#2Deike StrobelH-Index: 32
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Purpose: To investigate the spectrum, applicability and diagnostic capacity of intravenous contrast-enhanced ultrasound imaging (CEUS) in a pediatric population. Materials and Methods: From 08/2005 to 11/2015, n = 40 pediatric patients and young adults from 0 – 26 years (O 11.4 ± 7.5) and 3.0 – 85.3 kg (O 40.8 ± 25.6) with n = 55 investigations received n = 79 IV applications of ultrasound contrast agent (UCA). UCA dose and side effects were documented. Scanned organs were the liver (n = 42), sp...
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Transthoracic echocardiography and transesophageal echocardiography (TEE) are valuable for patients on extracorporeal membrane oxygenation (ECMO). These tools are used to perform “turn down” assessments, evaluate for cannula placement/position, and guide management. ECMO is a form of mechanical
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Background— The goal of this statement was to review the available literature on surveillance, screening, evaluation, and management strategies and put forward a scientific statement that would comprehensively review the literature and create recommendations to optimize neurodevelopmental outcome in the pediatric congenital heart disease (CHD) population. Methods and Results— A writing group appointed by the American Heart Association and American Academy of Pediatrics reviewed the available lit...
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#1Lanxin Du (Sichuan University)
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Neuroimaging is crucial in moyamoya disease (MMD) for neurosurgeons, during pre-surgical planning and intraoperative navigation not only to maximize the success rate of surgery, but also to minimize postsurgical neurological deficits in patients. This is a review of recent literatures which updates the clinical use of imaging methods in the morphological and hemodynamic assessment of surgical revascularization in patients with MMD. We aimed to assist surgeons in assessing the status of moyamoya ...
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When evaluating a child with a potential neurologic or neurodevelopmental disorder, identifying indications for imaging and the correct imaging modality to order can be challenging. This article provides an overview of computed tomography, MRI, ultrasonography, and radiography with an emphasis on indications for use, pitfalls to be avoided, and recent advances. A discussion of the appropriate use of ionizing radiation, intravenous contrast, and sedation is also provided.
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#1Memduha Gumus (University of Pittsburgh)
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Cranial US is an integral component of evaluating the neonatal brain, especially in the setting of critically ill infants and in the emergency setting, because cranial US can be performed portably at the bedside, is safe, and can be repeated whenever needed. Contrast-enhanced ultrasound (CEUS) involves intravenously injecting microbubbles to allow for improved visibility of large and small vessels to assess vascularity and is becoming a widespread technique to improve diagnostic performance of U...
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#1Judy H Squires (University of Pittsburgh)H-Index: 6
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Contrast-enhanced ultrasound (CEUS) utilization is expanding rapidly, particularly in children, in whom the modality offers important advantages of dynamic evaluation of the vasculature, portability, lack of ionizing radiation, and lack of need for sedation. Accumulating data establish an excellent safety profile of ultrasound contrast agents in children. Although only FDA-approved for IV use in children for characterizing focal liver lesions and for use during echocardiography, growing off-labe...
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Brain contrast-enhanced ultrasound (CEUS) is an emerging application that can complement gray-scale US and yield additional insights into cerebral flow dynamics. CEUS uses intravenous injection of ultrasound contrast agents (UCAs) to highlight tissue perfusion and thus more clearly delineate cerebral pathologies including stroke, hypoxic-ischemic injury and focal lesions such as tumors and vascular malformations. It can be applied not only in infants with open fontanelles but also in older child...
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