GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn
Abstract
Gastrin-releasing peptide (GRP) receptor-expressing (GRPR)+ neurons have a central role in the spinal transmission of itch. Because their fundamental regulatory mechanisms are not yet understood, it is important to determine how such neurons are excited and integrate itch sensation. In this study, we investigated the mechanisms for the activation of itch-responsive GRPR+ neurons in the spinal dorsal horn (SDH). GRPR+ neurons expressed the...
Paper Details
Title
GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn
Published Date
Jun 1, 2020
Journal
Volume
170
Pages
108025 - 108025
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