Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation
Abstract
Inflammation is a complex biological response to stimuli. Activated macrophages induced excessively release of pro-inflammatory cytokines and mediators such as endogenous radical nitric oxide (NO) play a significant role in the progression of multiple inflammatory diseases. Both natural and synthetic chalcones possess a wide range of bioactivities. In this work, thirty-nine chalcones and three related compounds, including several novel ones,...
Paper Details
Title
Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation
Published Date
May 1, 2020
Volume
193
Pages
112216 - 112216
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Notes
History