Original paper

A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors

Volume: 11, Issue: 1
Published: Feb 27, 2020
Abstract
Gram-negative bacteria deliver effectors via the type VI secretion system (T6SS) to outcompete their rivals. Each bacterial strain carries a different arsenal of effectors; the identities of many remain unknown. Here, we present an approach to identify T6SS effectors encoded in bacterial genomes of interest, without prior knowledge of the effectors’ domain content or genetic neighborhood. Our pipeline comprises a comparative genomics analysis...
Paper Details
Title
A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
Published Date
Feb 27, 2020
Volume
11
Issue
1
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