Improved inference for fixed‐effects meta‐analysis of 2 × 2 tables

Meta‐analysis of 2 × 2 tables is common and useful in research topics including analysis of adverse events and survey research data. Fixed‐effects inference typically centers on measures of association such as the Cochran‐Mantel‐Haenszel statistic or Woolf's estimator, but relies on assuming exact homogeneity across studies, which is often unrealistic. By showing that estimators of several widely‐used methods have meaningful estimands even in...