Heightened Dependence of Left-Heart Filling Pressures on Right-Heart Failure in Congenital Heart Disease

Background Pulmonary artery wedge pressure (PAWP) is often elevated in patients with right-sided congenital heart disease (CHD), raising the possibility of coexisting left-heart disease, but pressure-volume relationships in the left and right sides of the heart influence one another through interdependence, which may be amplified in patients with CHD. Methods We hypothesized that increases in PAWP in patients with CHD would be more strongly...