Beyond bacterial killing: NADPH oxidase 2 is an immunomodulator

Volume: 221, Pages: 39 - 48
Published: May 1, 2020
Abstract
NADPH oxidase 2 is a superoxide-generating enzymatic complex based on the catalytic subunit gp91phox that is also known as Nox2. Initially identified in neutrophils, NADPH oxidase 2 was long considered responsible only for the killing of phagocytized microorganisms. However, advances in knowledge about redox signalling and the discovery of Nox2 expression in different cell types, including macrophages, endothelial cells (ECs), dendritic cells...
Paper Details
Title
Beyond bacterial killing: NADPH oxidase 2 is an immunomodulator
Published Date
May 1, 2020
Volume
221
Pages
39 - 48
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