Thrombotic microangiopathy following heart transplant in pediatric Danon disease

This case describes an uncommon acute complication of diffuse thrombotic angiopathy and associated aHUS/TTP in an 11‐year‐old girl with Danon disease who underwent orthotopic heart transplant. Shortly after transplant, despite an uncomplicated operative course, the patient developed severe kidney injury and progressive altered mental status, culminating in cerebral edema, brain herniation, and death. She had received a single dose of tacrolimus...