Tubulin Proteins in Cancer Resistance: A Review
Abstract
Cancer cells are altered with cell cycle genes or they are mutated, leading to a high rate of proliferation compared to normal cells. Alteration in these genes leads to mitosis dysregulation and becomes the basis of tumor progression and resistance to many drugs. The drugs which act on the cell cycle fail to arrest the process, making cancer cell non-responsive to apoptosis or cell death. Vinca alkaloids and taxanes fall in this category and are...
Paper Details
Title
Tubulin Proteins in Cancer Resistance: A Review
Published Date
Jun 25, 2020
Journal
Volume
21
Issue
3
Pages
178 - 185
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