Protective Effect of Saponins-Enriched Fraction of <i>Gynostemma pentaphyllum</i> against High Choline-Induced Vascular Endothelial Dysfunction and Hepatic Damage in Mice
Volume: 43, Issue: 3, Pages: 463 - 473
Published: Mar 1, 2020
Abstract
Choline as a quaternary amine nutrient is metabolized to trimethylamine by gut microbiota and subsequently oxidized to circulating trimethylamine-N-oxide (TMAO), a gut-derived metabolite associated with liver toxicity and cardiovascular disease. The study was to probe the possible vasoprotective and hepatoprotective effects of total saponins of Gynostemma pentaphyllum (TSGP) in 3% high-choline water-feeding mice. The purified TSGP was obtained...
Paper Details
Title
Protective Effect of Saponins-Enriched Fraction of <i>Gynostemma pentaphyllum</i> against High Choline-Induced Vascular Endothelial Dysfunction and Hepatic Damage in Mice
Published Date
Mar 1, 2020
Volume
43
Issue
3
Pages
463 - 473
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