Eradication of planktonic Vibrio parahaemolyticus and its sessile biofilm by curcumin-mediated photodynamic inactivation

Vibrio parahaemolyticus is the leading pathogen in seafoods. This study established the efficient blue light-emitting diode (LED) photodynamic inactivation (PDI) to eradicate Vibrio parahaemolyticus and its biofilm with photosensitizer curcumin, and the antibacterial and antibiofilm mechanisms were elucidated by determining the DNA integrity, protein changes, morphological alteration, gene expression levels, chemical composition and structural...