Preparation of Conjugates for Affibody-Based PNA-Mediated Pretargeting.
Abstract
Affibody molecules are small engineered scaffold proteins suitable for in vivo tumor targeting. Radionuclide molecular imaging using directly radiolabelled affibody molecules provides excellent imaging. However, affibody molecules have a high renal reabsorption, which complicates their use for radionuclide therapy. The high renal reabsorption is a common problem for the use of engineered scaffold proteins for radionuclide therapy. Affibody-based...
Paper Details
Title
Preparation of Conjugates for Affibody-Based PNA-Mediated Pretargeting.
Published Date
Jan 1, 2020
Journal
Volume
2105
Pages
283 - 304
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History