Synthesis of selenylated polysaccharides from Momordica charantia L. and its hypoglycemic activity in streptozotocin-induced diabetic mice

Volume: 152, Pages: 295 - 304
Published: Jun 1, 2020
Abstract
In order to obtain the effective antidiabetic polysaccharide derivative, a selenylated polysaccharide (Se-MCPIIa-1), with an average molecular weight (MW) of 4.0038 × 104 Da, was synthesized by reduction of sodium selenite with ascorbic acid in the presence of Momordica polysaccharides (MCPIIa). The selenium (Se) content of Se-MCPIIa-1 was up to 445.0 μg/g, and its average diameter of monodisperse spherical particle size was around 63.78 nm. The...
Paper Details
Title
Synthesis of selenylated polysaccharides from Momordica charantia L. and its hypoglycemic activity in streptozotocin-induced diabetic mice
Published Date
Jun 1, 2020
Volume
152
Pages
295 - 304
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