Distinct microbial and immune niches of the human colon
Abstract
Gastrointestinal microbiota and immune cells interact closely and display regional specificity; however, little is known about how these communities differ with location. Here, we simultaneously assess microbiota and single immune cells across the healthy, adult human colon, with paired characterization of immune cells in the mesenteric lymph nodes, to delineate colonic immune niches at steady state. We describe distinct helper T cell activation...
Paper Details
Title
Distinct microbial and immune niches of the human colon
Published Date
Feb 17, 2020
Journal
Volume
21
Issue
3
Pages
343 - 353
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History