Investigations on the anti-aging activity of polysaccharides from Chinese yam and their regulation on klotho gene expression in mice

In this study, Chinese yam polysaccharides (CYP) were extracted from the tuber of Dioscorea opposita Thunb. by hot-water extraction and ethanol precipitation. After deproteinized by the Sevag method, the content of CYP was determined to be 91.77%. The anti-aging activities of the CYP were evaluated in aging mice induced by d-galactose in vitro and in vivo. The results indicated that the CYP not only could enhance the learning ability of mice,...