Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injury
Abstract
Research has attributed tissue damage post-traumatic brain injury (TBI) to two-pronged effects, increased reactive oxygen species (ROS) and impairment of endogenous antioxidant defence systems, underpinned by manganese superoxide dismutase (MnSOD). Novel antioxidant nitroxides have been shown to mimic MnSOD to ameliorate oxidative stress related disorders. This study aimed to investigate the effects of two nitroxides, CTMIO and DCTEIO, on the...
Paper Details
Title
Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injury
Published Date
Apr 1, 2020
Journal
Volume
97
Pages
57 - 65
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