Predicting Response to Rifaximin in Irritable Bowel Syndrome with Diarrhea: Is the Answer Blowing in the Wind?

Rezaie, A, Heimanson Z, McCallum R, et al. Lactulose breath testing as a predictor of response to rifaximin in patients with irritable bowel syndrome with diarrhea. Am J Gastroenterol 2019;114:1886–1893. Irritable bowel syndrome (IBS) is one of the most common functional bowel disorder worldwide (Clin Gastroenterol Hepatol 2012;10:712–721). The diagnosis is based on a patient reporting a specific combination of symptoms, as defined by the Rome...