Original paper

Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells

Volume: 21, Issue: 3, Pages: 321 - 330
Published: Feb 17, 2020
Abstract
Differentiation of CD4+ T cells into either follicular helper T (TFH) or type 1 helper T (TH1) cells influences the balance between humoral and cellular adaptive immunity, but the mechanisms whereby pathogens elicit distinct effector cells are incompletely understood. Here we analyzed the spatiotemporal dynamics of CD4+ T cells during infection with recombinant vesicular stomatitis virus (VSV), which induces early, potent neutralizing...
Paper Details
Title
Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells
Published Date
Feb 17, 2020
Volume
21
Issue
3
Pages
321 - 330
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