Validation and implementation of a modular targeted capture assay for the detection of clinically significant molecular oncology alterations
Abstract
The rapid discovery of clinically significant genetic variants has translated to next-generation sequencing assays becoming out-of-date by the time they are designed, validated, and implemented. UW-OncoPlex addresses this through the adoption of a modular panel capable of redesign as significant alterations are identified. We describe the validation of OncoPlex version 6 (OPXv6) for the detection of single nucleotide variants (SNVs), insertions...
Paper Details
Title
Validation and implementation of a modular targeted capture assay for the detection of clinically significant molecular oncology alterations
Published Date
Mar 1, 2020
Volume
19
Pages
e00153 - e00153
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