Control of Slc7a5 Sensitivity by the Voltage-Sensing Domain of Kv1 Channels

Voltage-gated potassium (Kv) channels are regulated by a variety of distinct accessory proteins, many of which remain to be identified. Additionally, the underlying mechanisms and physiological consequences of these interacting proteins as a complex with Kv channels remain poorly understood. Recently, we reported that the neutral amino acid transporter Slc7a5 has powerful regulatory effects on Kv1.2 channel gating and expression. In this study,...