Glycated albumin stimulates expression of inflammatory cytokines in muscle cells
Abstract
The effects of glycated albumin on the expression of inflammatory cytokines in differentiated myotubes were investigated. Glycated albumin stimulates the expression of TNF α, IL-1β, IL-6 and CCL-2 both at the mRNA and protein levels via the receptor of AGEs. Various cytokines demonstrated different kinetics of stimulation by glycated albumin. At a high glucose concentration, the stimulation effect was more pronounced than at a low one. At...
Paper Details
Title
Glycated albumin stimulates expression of inflammatory cytokines in muscle cells
Published Date
Apr 1, 2020
Journal
Volume
128
Pages
154991 - 154991
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