Mitochondria-targeting zeolitic imidazole frameworks to overcome platinum-resistant ovarian cancer
Abstract
Epithelial ovarian cancer is still the leading cause of death in gynecology due to its resistance to platinum-based first-line chemotherapeutic drugs. The utilization of mitochondria-targeted drugs has become an important direction in anti-tumor drug research and development. In this work, cisplatin (DDP)-loaded ZIF-90 with mitochondrial-targeting was synthesized at room temperature with a high drug loading (11.7 %, calculated based on Pt...
Paper Details
Title
Mitochondria-targeting zeolitic imidazole frameworks to overcome platinum-resistant ovarian cancer
Published Date
May 1, 2020
Volume
189
Pages
110837 - 110837
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