The Function of NM23-H1/NME1 and Its Homologs in Major Processes Linked to Metastasis
Abstract
Metastasis suppressor genes (MSGs) inhibit different biological processes during metastatic progression without globally influencing development of the primary tumor. The first MSG, NM23 (non-metastatic clone 23, isoform H1) or now called NME1 (stands for non-metastatic) was identified some decades ago. Since then, ten human NM23 paralogs forming two groups have been discovered. Group I NM23 genes encode enzymes with evolutionarily highly...
Paper Details
Title
The Function of NM23-H1/NME1 and Its Homologs in Major Processes Linked to Metastasis
Published Date
Jan 1, 2020
Volume
26
Issue
1
Pages
49 - 61
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