Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer
Abstract
BackgroundSmall cell lung cancer (SCLC) has a poor prognosis, and its treatment options are limited. Delta-like protein 3 (DLL3) is expressed specifically in SCLC and is considered a promising therapeutic target for patients with this disease. Rovalpituzumab tesirine (Rova-T) was the first antibody-drug conjugate targeting DLL3. Although Rova-T development was unfortunately terminated, DLL3 remains an ideal target for SCLC. Near infrared...
Paper Details
Title
Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer
Published Date
Feb 1, 2020
Journal
Volume
52
Pages
102632 - 102632
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