Biofabrication of a biomimetic supramolecular-polymer double network hydrogel for cartilage regeneration

Cartilage injury is difficult to self-heal due to avascular microenvironment and special mechanical properties. These features challenge the design of tissue engineered cartilage and repairing effect. In this study, a supramolecular-polymer double network (DN) hydrogel was designed to estimate the cartilage regeneration capability. This consisted of self-assembly of peptides supramolecular networks and covalent polymer networks together, and the...