Impaired functional capacity of polarised neonatal macrophages

Volume: 10, Issue: 1
Published: Jan 17, 2020
Abstract
Neonatal sepsis is accompanied by impaired apoptotic depletion of monocytes and macrophages (MΦ), aberrant cytokine production, impaired cell metabolism, and sustained inflammation. Macrophage-colony stimulating factor (M-CSF) triggers the differentiation from monocytes into MΦ (MΦ-0). Interleukin-10 (IL10) and Interferon-gamma (IFNy) further differentiate MΦ subpopulations, the anti-inflammatory MΦ-IL10 and the pro-inflammatory MΦ-IFNy subtype....
Paper Details
Title
Impaired functional capacity of polarised neonatal macrophages
Published Date
Jan 17, 2020
Volume
10
Issue
1
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