Pancreaticoduodenectomy for paraduodenal pancreatitis is associated with a higher incidence of diabetes but a similar quality of life and pain control when compared to medical treatment.

Published on Mar 1, 2020in Pancreatology3.629
· DOI :10.1016/J.PAN.2019.12.014
A. Balduzzi4
Estimated H-index: 4
(University of Verona),
Giovanni Marchegiani29
Estimated H-index: 29
(University of Verona)
+ 8 AuthorsClaudio Bassi110
Estimated H-index: 110
(University of Verona)
Abstract Background Paraduodenal pancreatitis is a focal form of chronic pancreatitis that affects the groove area between the duodenum and the head of the pancreas. Consensus regarding surgical or nonsurgical management as the best treatment option is still lacking. Methods We retrospectively evaluated all patients managed for PP at The Pancreas Institute of the University Hospital Trust of Verona from 1990 to 2017. The outcomes of surgical vs. medical treatment with regard to pain control, quality of life and pancreatic insufficiency were evaluated through specific questionnaires. Results The final study population consisted of 75 patients: 62.6% underwent surgery, and 37.4% were managed without surgery. All surgical procedures consisted of pancreaticoduodenectomy. The median follow-up from the diagnosis of paraduodenal pancreatitis was 60 (12–240) months. Patients who underwent surgery experienced a similar incidence of steatorrhea (44.7 vs. 52.6%; p = 0.4) but a significantly higher incidence of diabetes (59.6 vs. 10.7%; p  Conclusion In patients affected by paraduodenal pancreatitis, surgery and medical therapy seem to obtain similar results in terms of quality of life and pain control. However, surgery is associated with an increased prevalence of postoperative diabetes with consequent relevant issues with self-care management. Surgery should be considered only in selected patients after adequate medical treatment.
#1Fabiola Aguilera (Mayo Clinic)H-Index: 1
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Last. John A. Stauffer (Mayo Clinic)H-Index: 22
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BACKGROUND/AIMS: The operative management of groove pancreatitis (GP) is still a matter of controversy and pancreaticoduodenectomy (PD) can be a high-risk procedure for patients. The aim of this study was to report our 9-year experience of surgical resection for GP and to review relevant literature. METHODS: A retrospective review of patients undergoing pancreatectomy for GP from August 1, 2008, through May 31, 2017 was performed. Patients with clinical, radiologic, and final pathologic confirma...
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#1Liesbeth M Kager (ULB: Université libre de Bruxelles)H-Index: 1
Last. Marc G. BesselinkH-Index: 84
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#1Nicolò de Pretis (University of Verona)H-Index: 8
#2Fabiana CapuanoH-Index: 2
Last. Luca FrulloniH-Index: 58
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#1Luca Casetti (University of Verona)H-Index: 14
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