Virology

Antibody

Virulence

Immune system

Whooping cough

Biochemistry

Nasal administration

Receptor

Immunization

Attenuated vaccine

Microbiology

Bacteria

Biology

Gene

Vaccination

Immunity

Pertussis vaccine

G protein

Internal medicine

Antibody response

Immunology

Colonization

Bordetella pertussis

Pertussis toxin

Genetics

Medicine

Journal of Clinical Investigation

BACKGROUND. The live attenuated BPZE1 vaccine candidate induces protection against B. pertussis and prevents nasal colonization in animal models. Here we report on the responses in humans receiving a single intranasal administration of BPZE1.

Live attenuated pertussis vaccine BPZE1 induces a broad antibody response in humans