Determination of Computationally Efficient Multi-pool Model Fitting Approach for Pulsed Chemical Exchange Saturation Transfer MRI

Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is an emerging imaging technique that detects lowly-concentrated labile protons which can have many potential clinical applications. Multi-pool model fitting is a CEST quantification technique that is able to quantify the pure CEST effect of the individual labile proton pools for a more accurate analysis. However, multi-pool model fitting suffers from long...