Sensitive detection of choline in infant formulas by SERS marker transformation occurring on a filter-based flexible substrate

In this study, we developed a simple and sensitive surface-enhanced Raman scattering (SERS) technique for the detection of choline in infant formulas based on a filter-based flexible substrate. The flexible substrate with excellent SERS activity and reproducibility was fabricated using a syringe filter and Ag triangular nanoplates. The Raman marker, 3-mercaptophenylboronic acid, was oxidised to 3-hydroxythiophenol in the presence of H2O2, which...