Brainstem atrophy in the early stage of Alzheimer’s disease: a voxel-based morphometry study
Abstract
Postmortem studies on patients with Alzheimer’s disease (AD) have confirmed that the dorsal raphe nucleus (DRN) in the brainstem is the first brain structure affected in the earliest stage of AD. The present study examined the brainstem in the early stage of AD using magnetic resonance (MR) imaging. T1-weighted MR images of the brains of 81 subjects were obtained from the publicly available Open Access Series of Imaging Studies (OASIS) database,...
Paper Details
Title
Brainstem atrophy in the early stage of Alzheimer’s disease: a voxel-based morphometry study
Published Date
Jan 2, 2020
Journal
Volume
15
Issue
1
Pages
49 - 59
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