Glutamate-Weighted CEST Contrast After Removal of Magnetization Transfer Effect in Human Brain and Rat Brain with Tumor

To mitigate the effect of magnetization transfer (MT) from glutamate-weighted chemical exchange saturation transfer (GluCEST) contrast in healthy human brain and its demonstration in a rat brain tumor model. GluCEST data was acquired from six healthy human volunteers at 7T and on a rat brain with tumor at 9.4 T. Single voxel proton magnetic resonance spectroscopy (1HMRS) data was acquired from three human volunteers. The magnetic resonance...