Mechanisms of increased bioavailability through amorphous solid dispersions: a review
Abstract
Amorphous solid dispersions (ASDs) can increase the oral bioavailability of poorly soluble drugs. However, their use in drug development is comparably rare due to a lack of basic understanding of mechanisms governing drug liberation and absorption in vivo. Furthermore, the lack of a unified nomenclature hampers the interpretation and classification of research data. In this review, we therefore summarize and conceptualize mechanisms covering the...
Paper Details
Title
Mechanisms of increased bioavailability through amorphous solid dispersions: a review
Published Date
Dec 30, 2019
Journal
Volume
27
Issue
1
Pages
110 - 127
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