The Mitotic Apparatus and Kinetochores in Microcephaly and Neurodevelopmental Diseases
Abstract
Regulators of mitotic division, when dysfunctional or expressed in a deregulated manner (over- or underexpressed) in somatic cells, cause chromosome instability, which is a predisposing condition to cancer that is associated with unrestricted proliferation. Genes encoding mitotic regulators are growingly implicated in neurodevelopmental diseases. Here, we briefly summarize existing knowledge on how microcephaly-related mitotic genes operate in...
Paper Details
Title
The Mitotic Apparatus and Kinetochores in Microcephaly and Neurodevelopmental Diseases
Published Date
Dec 24, 2019
Journal
Volume
9
Issue
1
Pages
49 - 49
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