Biomarker discovery in cardiac allograft vasculopathy using targeted aptamer proteomics
Abstract
Cardiac allograft vasculopathy (CAV) limits long-term survival after heart transplantation. Non-invasive evaluation is challenging, and currently, there is no validated biomarker for CAV diagnosis or prognostication. To identify potential candidate CAV biomarkers, we utilized the Slow Off-rate Modified Aptamer (SOMAscan) assay, which evaluates over 1000 serum proteins, including many relevant to biological pathways in CAV. We evaluated three...
Paper Details
Title
Biomarker discovery in cardiac allograft vasculopathy using targeted aptamer proteomics
Published Date
Dec 30, 2019
Journal
Volume
34
Issue
1
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