Independent Methylome-Wide Association Studies of Schizophrenia Detect Consistent Case–Control Differences
Abstract
Methylome-wide association studies (MWASs) are promising complements to sequence variation studies. We used existing sequencing-based methylation data, which assayed the majority of all 28 million CpGs in the human genome, to perform an MWAS for schizophrenia in blood, while controlling for cell-type heterogeneity with a recently generated platform-specific reference panel. Next, we compared the MWAS results with findings from 3 existing...
Paper Details
Title
Independent Methylome-Wide Association Studies of Schizophrenia Detect Consistent Case–Control Differences
Published Date
Jun 5, 2019
Journal
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