Genomic and phenotypic characterization of a broad panel of patient-derived xenografts reflects the diversity of glioblastoma

Volume: 26, Issue: 5, Pages: 1094 - 1104
Published: Mar 1, 2020
Abstract
Purpose: null Glioblastoma is the most frequent and lethal primary brain tumor. Development of novel therapies relies on the availability of relevant preclinical models. We have established a panel of 96 glioblastoma patient-derived xenografts (PDX) and undertaken its genomic and phenotypic characterization. null Experimental Design: null PDXs were established from glioblastoma, IDH-wildtype (n = 93), glioblastoma, IDH-mutant (n = 2), diffuse...
Paper Details
Title
Genomic and phenotypic characterization of a broad panel of patient-derived xenografts reflects the diversity of glioblastoma
Published Date
Mar 1, 2020
Volume
26
Issue
5
Pages
1094 - 1104
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