Fast and binary assay for predicting radiosensitivity based on the theory of the ATM nucleoshuttling

Purpose or Objective The societal and clinical impact of post-radiotherapy Adverse Events (AE) have highlighted the need of molecular and cellular parameters that can predict the outcome of the treatment. Recent studies have stressed the role of the nucleoshuttling of the ATM protein in the response to radiation, and the statistical performances of this molecular endpoint to predict individual radiosensitivity. The purpose of this study was to...