Enzymatically crosslinked gelatin–laminin hydrogels for applications in neuromuscular tissue engineering
Abstract
We report a water-soluble and non-toxic method to incorporate additional extracellular matrix proteins into gelatin hydrogels, while obviating the use of chemical crosslinkers such as glutaraldehyde. Gelatin hydrogels were fabricated using a range of gelatin concentrations (4%-10%) that corresponded to elastic moduli of approximately 1 kPa-25 kPa, respectively, a substrate stiffness relevant for multiple cell types. Microbial transglutaminase...
Paper Details
Title
Enzymatically crosslinked gelatin–laminin hydrogels for applications in neuromuscular tissue engineering
Published Date
Jan 1, 2020
Journal
Volume
8
Issue
2
Pages
591 - 606
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