Multi-functional FITC-silica@gold nanoparticles conjugated with guar gum succinate, folic acid and doxorubicin for CT/fluorescence dual imaging and combined chemo/PTT of cancer
Abstract
A novel type of multi-functional fluorescein isothiocyanate (FITC)-silica (SiO2)@gold (Au) core-shell nanoparticles covered with folic acid (FA)-conjugated guar gum succinate (GGS) and doxorubicin (DOX) (FITC-SiO2@Au-DOX-GGS-FA NPs) was prepared for imaging and therapy of cancer. The physicochemical properties of these NPs were analyzed with 1H NMR, TEM and DLS. The FITC-SiO2@Au-DOX-GGS-FA NPs exhibited the fluorescence and X-ray attenuation...
Paper Details
Title
Multi-functional FITC-silica@gold nanoparticles conjugated with guar gum succinate, folic acid and doxorubicin for CT/fluorescence dual imaging and combined chemo/PTT of cancer
Published Date
Feb 1, 2020
Volume
186
Pages
110701 - 110701
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