Oleanane- type saponins from Glochidion glomerulatum and their cytotoxic activities
Abstract
Eight oleanane-type saponins, glomerulosides A-H, were isolated from leaves of Glochidion glomerulatum. All isolated compounds were evaluated for cytotoxic activity on four human cancer cell lines, A-549, HT-29, OVCAR, and MCF-7. Glomerulosides C and E, which contain a benzoyloxy group at C-22, showed significant cytotoxic activities against the A-549, HT-29, and OVCAR cancer cell lines with IC50 values ranging from 5.9 to 9.8μM. Glomeruloside A...
Paper Details
Title
Oleanane- type saponins from Glochidion glomerulatum and their cytotoxic activities
Published Date
Aug 1, 2015
Journal
Volume
116
Pages
213 - 220
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