Chaperone activity of serine protease HtrA of Helicobacter pylori as a crucial survival factor under stress conditions

Volume: 17, Issue: 1
Published: Dec 1, 2019
Abstract
Background Serine protease HtrA exhibits both proteolytic and chaperone activities, which are involved in cellular protein quality control. Moreover, HtrA is an important virulence factor in many pathogens including Helicobacter pylori , for which the crucial stage of infection is the cleavage of E-cadherin and other cell-to-cell junction proteins. Methods The in vitro study of H. pylori HtrA (HtrA Hp ) chaperone activity was carried out using...
Paper Details
Title
Chaperone activity of serine protease HtrA of Helicobacter pylori as a crucial survival factor under stress conditions
Published Date
Dec 1, 2019
Volume
17
Issue
1
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