Targeting senescent cells: approaches, opportunities, challenges
Abstract
Cellular senescence is a hallmark of aging, whose onset is linked to a series of both cell and non-cell autonomous processes, leading to several consequences for the organism. To date, several senescence routes have been identified, which play a fundamental role in development, tumor suppression and aging, among other processes. The positive and/or negative effects of senescent cells are directly related to the time that they remain in the...
Paper Details
Title
Targeting senescent cells: approaches, opportunities, challenges
Published Date
Nov 30, 2019
Journal
Volume
11
Issue
24
Pages
12844 - 12861
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Notes
History