Window of opportunity clinical trial designs to study cancer metabolism
Abstract
Window of opportunity trials exploit the ‘window’ of time after cancer diagnosis, typically prior to initiation of cancer therapy. In recent years this study design has become a more regular feature of drug development, as this ‘window’ provides an opportunity to carry out a thorough pharmacodynamic assessment of a therapy of interest in tumours that are unperturbed by prior treatment. Many of the first window trials interrogated the bioactivity...
Paper Details
Title
Window of opportunity clinical trial designs to study cancer metabolism
Published Date
Dec 10, 2019
Journal
Volume
122
Issue
1
Pages
45 - 51
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