Development of cancer metabolism as a therapeutic target: new pathways, patient studies, stratification and combination therapy
Abstract
Cancer metabolism has undergone a resurgence in the last decade, 70 years after Warburg described aerobic glycolysis as a feature of cancer cells. A wide range of techniques have elucidated the complexity and heterogeneity in preclinical models and clinical studies. What emerges are the large differences between tissues, tumour types and intratumour heterogeneity. However, synergies with inhibition of metabolic pathways have been found for many...
Paper Details
Title
Development of cancer metabolism as a therapeutic target: new pathways, patient studies, stratification and combination therapy
Published Date
Dec 10, 2019
Journal
Volume
122
Issue
1
Pages
1 - 3
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Notes
History