Cancer

Internal medicine

Surgery

Political science

Systematic review

Asthma

Sinusitis

Functional endoscopic sinus surgery

Colonoscopy

MEDLINE

Polypectomy

Nasal polyps

Endoscopic sinus surgery

Chronic rhinosinusitis

Confidence interval

Colorectal cancer

Medicine

Meta-analysis

International Forum of Allergy & Rhinology

Wide variations in revision endoscopic sinus surgery (ESS) rates for chronic rhinosinusitis with nasal polyposis (CRSwNP) have been reported. It is important to understand expected revision rates and factors that impact the need for revision.A literature search was conducted on PubMed, Scopus, and the Cochrane Database of Systematic Reviews. Following PRISMA guidelines, a systematic review and meta-analysis was performed on studies that reported revision surgery data for CRSwNP patients.Forty-five studies with 34,220 subjects were meta-analyzed, with an overall revision rate of 18.6% (95% confidence interval, 14.1%-23.6%). Studies with extractable follow-up data reported a mean revision rate of 16.2% over a weighted mean follow-up of 89.6 months. Factors associated with increased revision rates included allergic fungal rhinosinusitis (28.7%), aspirin-exacerbated respiratory disease (27.2%), asthma (22.6%), prior polypectomy (26.0%), and publication prior to 2008 (22.7%) (p < 0.05 for all).Although polyps can recur after ESS, reported long-term ESS revision rates are approximately 14% to 24%. Identifying risk factors for revision surgery can help manage patient expectations and determine optimal personalized treatments.

Revision surgery rates in chronic rhinosinusitis with nasal polyps: meta‐analysis of risk factors