Significance of RAS mutations in pulmonary metastases of patients with colorectal cancer

Volume: 25, Issue: 4, Pages: 641 - 650
Published: Nov 26, 2019
Abstract
RAS/BRAF mutations of colorectal cancer (CRC) play a crucial role in carcinogenesis and cancer progression and need to be considered for the therapeutic strategy choice. We used next-generation-sequencing (NGS) technology to assess RAS/BRAF mutation differences between primary CRC and corresponding pulmonary metastases (PMs). We examined the mutation statuses of the KRAS 12/13/61/146, NRAS 12/13/61/146, and BRAF 600 codons in genomic DNA from...
Paper Details
Title
Significance of RAS mutations in pulmonary metastases of patients with colorectal cancer
Published Date
Nov 26, 2019
Volume
25
Issue
4
Pages
641 - 650
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