Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging.

Volume: 29, Issue: 12, Pages: 2088 - 2103
Published: Nov 21, 2019
Abstract
Aging is a pleiotropic process affecting many aspects of mammalian physiology. Mammals are composed of distinct cell type identities and tissue environments, but the influence of these cell identities and environments on the trajectory of aging in individual cells remains unclear. Here, we performed single-cell RNA-seq on >50,000 individual cells across three tissues in young and old mice to allow for direct comparison of aging phenotypes across...
Paper Details
Title
Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging.
Published Date
Nov 21, 2019
Volume
29
Issue
12
Pages
2088 - 2103
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