Polygenic risk of psychiatric disorders exhibits cross-trait associations in electronic health record data
Abstract
null Objective null Prediction of disease risk is a key component of precision medicine. Common, complex traits such as psychiatric disorders have a complex polygenic architecture making the identification of a single risk predictor difficult. Polygenic risk scores (PRS) denoting the sum of an individual’s genetic liability for a disorder are a promising biomarker for psychiatric disorders, but require evaluation in a clinical setting. null...
Paper Details
Title
Polygenic risk of psychiatric disorders exhibits cross-trait associations in electronic health record data
Published Date
Nov 29, 2019
Journal
Pages
858027
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